UY Psilocybin law · Americas · Reviewed Nov 12, 2026
As of November 2026, personal-use possession of psilocybin in Uruguay is exempt from criminal liability, but unauthorized production and commercial supply remain criminal offences.
Article 31 of Decreto-Ley 14.294 exempts possession of a quantity intended for personal consumption from liability; a judge assesses the intended use case by case, and there is no fixed quantity limit for psilocybin. Possession not considered for personal consumption can be prosecuted.
Psilocybin and psilocin are controlled substances. Unauthorized production carries 2–10 years’ imprisonment, while sale and other listed trafficking conduct can carry 2–12 years. The sources do not establish separate rules for spores or grow kits; they also note that the controlled-substances list names the alkaloids, not the mushrooms themselves.
There is no operating legal therapy or compassionate-use pathway. An ethics-authorized study received approval in 2023, but researchers said it had not started by mid-2026 and was awaiting funding.
The sources describe no lawful retail supply or regulated psilocybin retreat program. Personal-use possession is assessed case by case, so the exemption should not be taken as permission to buy or sell mushrooms.
Uruguay’s research ethics commission authorized the clinical phase of a proposed psilocybin study.
Decreto 198/025 replaced the consolidated controlled-substances list; its List I includes psilocybin and psilocin.
A June legal-status correction classified Uruguay as decriminalized rather than legal, noting that personal-use possession is exempt but sale and production remain crimes.
Sources reviewing the law in August–October reiterated that personal-use quantity is determined by a judge and that no legal therapy pathway was operating.
Number of countries in each category. Uruguay’s category is highlighted.
Access score from 0 (illegal) to 5 (legal or openly sold).
Browse cities across Uruguay and see the nearest listings on the map.
Listings describe themselves; Pscilly does not sell psilocybin, and sellers without a government licence are labeled “not licensed.”
As of November 2026, personal-use possession of psilocybin in Uruguay is exempt from criminal liability, but unauthorized production and commercial supply remain criminal offences.
Article 31 of Decreto-Ley 14.294 exempts possession of a quantity intended for personal consumption from liability; a judge assesses the intended use case by case, and there is no fixed quantity limit for psilocybin. Possession not considered for personal consumption can be prosecuted.
Psilocybin and psilocin are controlled substances. Unauthorized production carries 2–10 years’ imprisonment, while sale and other listed trafficking conduct can carry 2–12 years. The sources do not establish separate rules for spores or grow kits; they also note that the controlled-substances list names the alkaloids, not the mushrooms themselves.
There is no operating legal therapy or compassionate-use pathway. An ethics-authorized study received approval in 2023, but researchers said it had not started by mid-2026 and was awaiting funding.
The sources describe no lawful retail supply or regulated psilocybin retreat program. Personal-use possession is assessed case by case, so the exemption should not be taken as permission to buy or sell mushrooms.
Pscilly classifies Uruguay as: personal possession decriminalized. Laws change often, so check the linked sources and current local rules.
Educational summary, not legal advice. Pscilly reviewed these laws on November 12, 2026 using the sources listed; laws and enforcement change often, so confirm current rules with local authorities or a lawyer before you travel. Never carry psilocybin across a border.
Pscilly is a mushroom directory and marketplace for the U.S., Canada, Europe and beyond, covering mushroom shops, licensed psilocybin centers, smart shops, retreats, mushroom brands, delivery services, events and deals. Listings come from the businesses themselves and from public sources, and every listing links to the business.